Saint Dominic Receives the Rosary

Sister Plautilla Nelli (1524–1588) was a self-taught nun-artist and the first ever known female Renaissance painter of Florence. She was a nun of the Dominican convent of St. Catherine of Siena located in Piazza San Marco, Florence, and was heavily influenced by the teachings of Savonarola and by the artwork of Fra Bartolomeo.

Pulisena Margherita Nelli was born into a wealthy family in the San Felice area of Florence. Her father, Piero di Luca Nelli, was a successful fabric merchant and her ancestors originated from the Tuscan valley area of Mugello, as did the Medici dynasty. There is a modern-day street in Florence, Via del Canto de' Nelli, in the San Lorenzo district, named for her family, and the New Sacristy of the Church of San Lorenzo is the original site of her family homes.

She became a nun at the age of fourteen, taking on the name Suor Plautilla, at the convent of Santa Caterina di Cafaggio; she would later be prioress on three occasions. The facility was managed by the Dominican friars of San Marco, led by Savonarola. About half of all educated girls in that era were placed into convents to avoid the cost of raising a dowry.